September 19, 2021

elprincipelila

There's nothing like our health

New epilepsy supplement shows good tolerance and reduces seizures

3 min read

The ketogenic diet (KD) involves a strict regiment of high-fat, low-carbohydrate and adequate protein consumption. By engaging in the diet, the body enters into the fasting state, altering metabolism and activating the process of burning fat and producing ketones for use as its primary fuel source.

KD is a popular dietary treatment for drug-resistant epilepsies. However, it is known to have side effects including constipation, low blood sugar, and stomach problems, along with challenges such as a lack of suitability for everyone and poor compliance.

Discovering a new supplement

K.Vita, also known as Betashot, is an oral liquid dietary supplement developed by University College London (UCL) in collaboration with Royal Holloway, University of London, and Vitaflo International.

The new supplement is the result of novel findings by UCL researchers, who discovered a different underlying mechanism to explain the KD’s effectiveness against epilepsy. In producing a new treatment, the researchers also strived to minimise the adverse side effects of undertaking a KD.

Keto diets and severe epilepsy

Motivated by their previous investigation into the mechanisms that indicate how KD works in epilepsy, in this study, the researchers sought to understand the impact and role a KD has on severe epilepsy in adults and children.

“We evaluated a newly developed medium chain triglyceride (type of dietary fat) supplement, designed to increase levels of decanoic acid, while also reducing the adverse side effects, and to be more palatable,” ​states Professor Matthew Walker, National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology. “The idea being that by avoiding (or reducing) the ketones, we could have a better-tolerated diet that would require much less specialist dietician input.”

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